Bulletin of Rehabilitation MedicineBulletin of Rehabilitation Medicine2078-19622713-2625National Medical Research Center for Rehabilitation and Balneology59572810.38025/2078-1962-2023-22-2-32-41Research ArticlePsychometric Approbation of Screening Methods for the Diagnosis of Cognitive Status in a Sample of Ischemic Stroke Patients: an Observational Cohort StudyKotelnikovaAnastasia V.<p>Ph.D. (Psycol.), Senior Researcher</p>pav-kotelnikov@yandex.ruhttps://orcid.org/0000-0002-9605-557XPogonchenkovaIrena V.<p>Dr. Sci. (Med.), Director</p>pogonchenkovaiv@zdrav.mos.ruhttps://orcid.org/0000-0001-5123-5991KostenkoElena V.<p>Dr. Sci. (Med.), Professor, Chief Scientific Officer Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of Moscow Healthcare Department; Neurologist, Professor of the Department of Neurology, Neurosurgery and Medical Genetics, Pirogov Russian National Research Medical University</p>ekostenko58@mail.ruhttps://orcid.org/0000-0003-0902-348XPetrovaLiudmila V.<p>Ph.D. (Med.), Senior Researcher, Neurologist, Head of Department of Medical Rehabilitation</p>ludmila.v.petrova@yandex.ruhttps://orcid.org/0000-0003-0353-553XKhaustovaAnna V.<p>Medical Psychologist</p>anchentodd@gmail.comhttps://orcid.org/0000-0001-9559-235XMoscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine of Moscow Healthcare DepartmentPirogov Russian National Research Medical University2409202322232412409202324092023Copyright © 2023, Kotelnikova A.V., Pogonchenkova I.V., Kostenko E.V., Petrova L.V., Khaustova A.V.2023<p><strong>INTRODUCTION.</strong> Cognitive disorders (CD) are the leading causes of disability and worsening of the quality of life of after-stroke patients. An important task is the validation of the scales for screening and diagnosis of CD.</p> <p><strong>AIM. </strong>To estimate the validity of screening methods for measuring cognitive functions (MMSE, МоСА) on a sample of patients with ischemic stroke (IS).</p> <p><strong>MATERIAL AND METHODS.</strong> We examined 105 patients with IS (stroke duration 2.7 1.9 months) and studied various types of validity, reliability and differentiating capabilities of test scales. As an external criterion, the data of the methodology Brief neuropsychological Cognitive examination (BNCE) were used. The conditions of applicability of the tests were investigated by comparative analysis of data with patients of the comparison group (n = 100) with diseases of the musculoskeletal system.</p> <p><strong>RESULTS. </strong>The МоСА and MMSE tests had high indicators of substantive validity and internal consistency of the scales (-Kronbach: 0.95 for МоСА and 0.92 for MMSE). The discriminative capabilities of the techniques are limited: there are discrepancies in the screening results compared to the BNCE data: МоСА tends to overdiagnose pronounced cognitive impairment (CI), MMSE showed low sensitivity to pronounced CI and a tendency to overestimate the number of cases of absence of CI. The revision of the test standards was justified by direct extrapolation of the boundaries of the quantitative interpretation of various levels of CI according to the BNCE to the tested scales and showed high competitive capabilities of the МоСА in the screening study of cognitive status.</p> <p><strong>CONCLUSION.</strong> Various types of validity and reliability of scales were studied, the method of quantitative interpretation was modified, and new test standards for MMSE and MoCA were developed. 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