Issue 2-90, 2019

Coordination disorders in patients with osteoporotic compression vertebral fractures

View article (Download PDF file)



Download XML file

1 Makarova E.V., 1 Marchenkova L.A., 1 Shakurova L.R., 1 Eremushkin M.A., 1 Styazkina E.M., 1 Chesnikova E.I., 2 Novikov A.V., 2 Malysheva T.B.

1 «National Medical Research Center of Rehabilitation and Balneology», Moscow, Russia
2 «University Clinic of Privolzhsky Research Medical University», Nizhny Novgorod, Russia


ABSTRACT

The aim of our study was to evaluate coordination disorders and identify associated risk factors in patients withosteoporosis (OP) with vertebral compression fractures (VF). The study group consisted of 60 people aged 65.43 ± 7.12 yearswith osteoporotic VF. The control group included 30 people aged 61.97 ± 5.22 years with OP without VF. Bone mineral densityusing stabilometry, functional tests, level 25 (OH) D3 was evaluated. In patients with VFs coordination abilities were lowerthan in individuals without fractures: according to stabilometry, a lower balance coefficient was found with open (p = 0.000)and closed eyes (p=0.03), a greater displacement and greater medio-lateral deviation (p=0.01 and p=0.025), lower speed ofcenter of pressure (CP) displacement (p=0.01). Patients in the main group maintained poor balance standing on left leg withopen (p=0.05) and closed eyes (p = 0.05) in One-leg-standing test, and also had significant deviation to the side in Fukuuda-Unterberger test (p=0.02). Conclusions: 1) OP, regardless of the presence of VF, leads to poor coordination abilities. 2) Thefunctions of static and dynamic balance suffer, a shift in the center of gravity is observed. 3) The presence of VFs in OP leadsto a more pronounced decrease in patient coordination abilities. 4) Multiple VFs, advanced age, low body weight, durationof menopause, a decrease in the level of 25 (OH) D3 – factors associated with impaired coordination in patients with OP.


KEYWORDS: osteoporosis, vertebral fractures, coordination, balance, falls, rehabilitation, postural disorders.


References:

  1. Peterka RJ, Black FO (1990-91) Age-related changes in human posture control: sensory organization tests. J Vestib Res 1:73-854
  2. WHO. Falls fact sheet. http://www.who.int/ mediacentre/factsheets/fs344/en/ (updated sept 2016).
  3. Lesnyak O.M. Padeniya kak vazhnaya sostavnaya chast’ problemy perelomov u pozhilyh lyudej // «RMZH» №17 ot 05.08.2008
  4. Susan C Slade, David L Carey, Anne-Marie Hill, Meg E Morris. Effects of falls prevention interventions on falls outcomes for hospitalised adults: pro- tocol for a systematic review with meta-analysis. BMJ Open. 2017; 7(11): e017864. doi: 10.1136/bmjopen-2017-017864 PMCID: PMC5695509PMID: 29133324
  5. Wei-Li Hsu a,b, Chao-Yin Chen b, Jau-Yih Tsauo a,b, Rong-Sen Yang c, Balance control in elderly people with osteoporosis // Journal of the Formosan Medical Association (2014) 113, 334-339
  6. Elena Volpi, Reza Nazemi, and Satoshi Fujita. Muscle tissue changes with aging. Curr Opin Clin Nutr Metab Care. 2004 Jul; 7(4): 405-410. PMCID: PMC2804956 NIHMSID: NIHMS131937
  7. Parreira PCS, Maher CG, Megale RZ. An overview of clinical guidelines for the management of vertebral compression fracture: a systematic review. Spine J. 2017 Dec;17(12):1932-1938. doi: 10.1016/j.spinee.2017.07.174.
  8. Marchenkova L.A., Prohorova E.A., Dreval’ A.V., Polyakova E.YU., Petuhova N.YU., Vishnyakova M.V. Vliyanie postmenopauzal’nogo osteoporoza i subklinicheskih kompressionnyh perelomov pozvonkov na kachestvo zhizni zhenshchin v postmenopauze // Al’manah klinicheskoj mediciny. 2014. № 32. S. 43-49.
  9. Prohorova E.A., Dreval’ A.V., Marchenkova L.A. Vzaimosvyaz’ osteoporoza so snizheniem kachestva zhizni i psihoehmocional’nymi narusheniyami // Rossijskij medicinskij zhurnal. 2012. № 4. S. 50-53.
  10. Marchenkova L.A. Postmenopauzal’nyj osteoporoz kak mediko-social’naya i ehkonomicheskaya problema XXI v. // Farmateka. 2015. № S4. S. 13-21.
  11. Mel’nichenko G.A., Belaya ZH.E., Rozhinskaya L.YA., Toropcova N.V., Alekseeva L.I., Biryukova E.V., Grebennikova T.A., Dzeranova L.K., Dreval’ A.V., Zagorodnij N.V., Il’in A.V., Kryukova I.V., Lesnyak O.M., Mamedova E.O., Nikitinskaya O.A., Pigarova E.A., Rodionova S.S., Skripnikova I.A., Tarbaeva N.V., Farba L.YA., Coriev T.T., CHernova T.O., YUreneva S.V., YAkushevskaya O.V., Dedov I.I. Federal’nye klinicheskie rekomendacii po diagnostike, lecheniyu i profilaktike osteoporoza. // Problemy ehndokrinologii. 2017. T. 63. №6. S. 392—426. doi: 10.14341/probl2017636392-426
  12. H. K. Genant, C. Y. Wu, C. van Kuijk, and M. C. Nevitt. Vertebral fracture assessment using a semiquantitative technique. Journal of Bone and Mineral Research 8, pp. 1137-1148, Sep 1993. Proc. of SPIE Vol. 6512 651219-8
  13. Grohovskij S.S., Kubryak O.V., Filatov I.A. Arhitektura setevyh medicinskih sistem dlya ocenki funkcii ravnovesiya (stabilometriya) i kompleksnoj ocenki sostoyaniya cheloveka // Informacionno-izmeritel’nye i upravlyayushchie sistemy, izdatel’stvo Radiotekhnika (M.), tom 9, № 12, s. 68-74.
  14. Pankova I.A., Krivoshej I.V., Kubryak O.V. Mery povysheniya ehffektivnosti upravleniya processom reabilitacii s ispol’zovaniem stabiloplatformy // Kremlevskaya medicina. Klinicheskij vestnik, tom 2, № 4, s. 153-156
  15. Eremushkin M.A. Dvigatel’naya aktivnost’ i zdorov’e. Ot lechebnoj gimnastiki do parkura. «Sport» - 2016 g. 240 str.
  16. Haines T., Kuys S.S., Morrison G., et al. impairment not predictive of falls in geriatric rehabilitation wards. J. Gerontol. Biol. Sci. Med. Sci. 2008;63:523-28. Doi: 10.1093/ gerona/63.5.523.
  17. Abreu DC, Trevisan DC, Costa GC, Vasconcelos FM, Gomes MM, Carneiro AA. The association between osteoporosis and static balance in elderly women // Osteoporosis international. — 2010. — Vol. 21. — No 9. — R. 1487-1491.
  18. Mendy A., Vieira ER, Albatineh AN, Nnadi AK, Lowry D, Gasana J. Low bone mineral density is associated with balance and hearing impairments // Annals of Epidemiology Volume 24, Issue 1, January 2014, Pages 58-62
  19. Nguyen Vu H. Osteoporosis prevention and osteoporosis exercise in community-based public health programs // Osteoporosis and Sarcopenia 3 (2017) 18e31
  20. Staggs V.S., Mion L.C., Shorr R.I. Assisted and unassisted falls: different events, different outcomes, different implications for quality of hospital care. Jt. Comm. J. Qual. Patient. Saf. 2014;40:358-64. Doi:10.1016/S1553- 7250(14)40047-3.
  21. Marchenkova L.A. Covremennye rekomendacii i standarty po diagnostike deficita vitamina D i ego lecheniyu // Sovremennye algoritmy diag-nostiki i lecheniya nejroehndokrinnyh zabolevanij po materialam 97-j Ezhegodnoj konferencii Amerikanskogo obshchestva ehndokrinologov (ENDO 2015) i Evropejskogo ehndokrinologicheskogo kongressa : materialy Oblastnoj mezhdisciplinarnoj nauchno-prakticheskoj konferencii. 2015. S. 17-19.
  22. Marchenkova L.A. Patogeneticheskoe obosnovanie primeneniya al’fakal’cidola dlya lecheniya osteoporoza pri nekotoryh ehndokrinnyh zabol-evaniyah // EHffektivnaya farmakoterapiya. 2015. № 46. S. 20-27.
  23. Kubryak O. V., Grohovskij S. S., Dobrorodnyj A. V. Issledovanie opornyh reakcij cheloveka (posturografiya, stabilometriya) i biologicheskaya obrat-naya svyaz’ v programme STPL. // Mera-TSP. Moskva, 2018. — 121 s.
  24. Marchenkova L.A., Makarova E.V., Eremushkin M.A. Medicinskaya reabilitaciya pacientov s osteoporozom, oslozhnennym perelomami. // Moskva - OOO «Torus Press» 113 s.
  25. Makarova E.V., Marchenkova L.A., Eremushkin M.A., Styazhkina E.M., CHesnikova E.I., Novikov A.V. EHffektivnost’ trenirovok glubokoj stabilizacionnoj sistemy pozvonochnika u pacientov s kompressionnymi perelomami pozvonkov na fone osteoporoza // Travma 2018: mul’tidisciplinarnyj podhod sbornik tezisov Mezhdunarodnoj konferencii. Rossijskij nacional’nyj issledovatel’skij medicinskij universitet im. N. I. Pirogova. 2018. S. 180-181.
  26. Marchenkova L.A., Makarova E.V. EHffektivnye vozmozhnosti profilaktiki padenij i perelomov u pacientov s osteoporozom: fokus na kompleksnyj podhod // Farmateka. 2018. № S2. S. 6-11.



Creative Commons License
The content is available under the Creative Commons Attribution 4.0 License.

©


This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.