Issue №2-22, 2023

Original article

The impact of secondary prevention methods on medication adherence in cardiac rehabilitation of patients after catheter ablation: a Prospective Study



1 ORCIDViktoriya А. Badtieva 2,3 ORCIDNana V. Pogosova 1 ORCIDAnastasiya I. Ovchinnikova

1Moscow Scientific-Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
2Federal State Budget Organization «National Medical Research Centre of Cardiology named after Academician E.I. Chazov» of the Ministry of Health of the Russian Federation
3Peoples’ Friendship University of Russia named after Patrice Lumumba


ABSTRACT

INTRODUCTION. Medication non-adherence is one of the significant public health issue. Low adherence is one of the main reasons for the decrease therapeutic effect in patients with atrial fibrillation (AF), development of complications of AF, which leads to poor health outcomes and increased healthcare costs. Secondary prevention programs in cardiac rehabilitation may improve medication adherence in patients with AF.

AIM. To assess the impact of secondary prevention methods on medication adherence in patients after catheter ablation (CA) performed for paroxysmal AF.

MATERIALS AND METHODS. This is a prospective randomized controlled study with 3 parallel groups of patients with paroxysmal AF after CA (radiofrequency or cryoablation). Patients were randomized into 3 groups in 1:1:1 ratio. The 2 intervention groups received secondary prevention methods, including single-session in-person counseling and for 3 months of distant support (by phone in Group 1 or by e-mail in Group 2). Group 3 received usual care. Medication adherence was assessed using the 4-question scale Moriscos-Green. The medication adherence was evaluated at baseline and 12 months after CA.

RESULTS AND DISCUSSION. A total of 135 patients aged 35 to 79 years were enrolled (mean age 57 ± 9 years, 51,8 % men). At 1 year of follow-up patients from intervention group experienced significant improvement of medication adherence (p = 0,006 for Group 1 и 2) vs control.

CONCLUSION. Secondary prevention methods with remote support improve the medication adherence in AF pts after CA which may positively affect on their health.


KEYWORDS: secondary prevention, cardiac rehabilitation, atrial fibrillation, medication adherence, distant support, catheter ablation

Acknowledgments: The study had no sponsorship.

Conflict of interest:: The authors declare no apparent or potential conflicts of interest related to the publication of this article.

For citation:

Badtieva V.A., Pogosova N.V., Ovchinnikova A.I. The impact of secondary prevention methods on medication adherence in cardiac rehabilitation of patients after catheter ablation: a Prospective Study. Bulletin of Rehabilitation Medicine. 2023; 22(2):120-128. https://doi.org/10.38025/2078-1962-2023-22-2-120-128 (In Russ.).



References:

  1. Boytsov S. A., Pogosova N. V., Ansheles A. A., Badtieva V. A., Balakhonova T. V., Barbarash O. L., Vasyuk Yu.A., Gambaryan N. G., Gendlin G. E., Golitsyn S. P., Drapkina O. M., Drozdova L.Yu., Yezhov M. V., Ershova A. I., Zhirov I. V., Karpov Yu.A., Kobalava Z. D., Kontsevaya A. V., Litvin A.Yu., Lukyanov M. M., Martsevich S.Yu., Matskeplishvili S. T., Metelskaya V. A., Meshkov A. N., Mishina I. E., Panchenko E. P., Popova A. B., Sergienko I. V., Smirnova M. D., Smirnova M. I., Sokolova O.Yu., Starodubova A. V., Sukhareva O.Yu., Ternovoy S. K., Tkacheva O. N., Shalnova S. A., Shestakova M. V. Cardiovascular prevention 2022. Russian national guidelines. Russian Journal of Cardiology. 2023; 28(5): 5452. https://doi.org/10.15829/1560-4071-2023-5452 (In Russ.).
  2. Belenkov Yu. N. Kardiologiya. Natsional’noe rukovodstvo. Moscow. GEHOTAR-Media. 2010: 629 p. (In Russ.).
  3. Ferrari R., Bertini M., Blomstrom-Lundqvist C. et al. An update on atrial fibrillation in 2014: From pathophysiology to treatment. International Journal of Cardiology. 2016; (203): 22–9. https://doi.org/10.1016/j.ijcard.2015.10.089
  4. Friberg L., Rosenqvist M., Lindgren A. et al. High prevalence of atrial fibrillation among patients with ischemic stroke. Stroke. 2014; 45(9): 2599–605. https://doi.org/10.1161/STROKEAHA.114.006070
  5. Lau D. H., Nattel S., Kalman J. M. et al. Modifiable Risk Factors and Atrial Fibrillation. Circulation. 2017; 136(6): 583–596. https://doi.org/10.1161/CIRCULATIONAHA.116.023163
  6. Rottner L., Bellmann B., Lin T. et al. Catheter Ablation of Atrial Fibrillation: State of the Art and Future Perspectives. Cardiology and Therapy. 2020; 9(1): 45–58. https://doi.org/10.1007/s40119-019-00158-2
  7. Keteyian S. J., Ehrman J. K., Fuller B. et al. Exercise Testing and Exercise Rehabilitation for Patients with Atrial Fibrillation. Journal of Cardiopulmonary Rehabilitation and Prevention. 2019; 39(2): 65–72. https://doi.org/10.1097/HCR.0000000000000423
  8. Younis A., Shaviv E., Nof E. et al. The role and outcome of cardiac rehabilitation program in patients with atrial fibrillation. Clinical Cardiology. 2018; 41(9): 1170–1176. https://doi.org/10.1002/clc.23001
  9. Lin J. S., O’Connor E.A., Evans C. V. et al. Behavioral Counseling to Promote a Healthy Lifestyle for Cardiovascular Disease Prevention in Persons with Cardiovascular Risk Factors: An Updated Systematic Evidence Review for the U. S. Preventive Services Task Force [Internet]. Rockville (MD). Agency for Healthcare Research and Quality (US). 2014.
  10. Umpierre D., Ribeiro P. A., Kramer C. K. et al. Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. JAMA. 2011; 305(17): 1790–9. https://doi.org/10.1001/jama.2011.576
  11. Varnfield M., Karunanithi M., Lee C. K. et al. Smartphone-based home care model improved use of cardiac rehabilitation in postmyocardial infarction patients: results from a randomised controlled trial. Heart. 2014; 100(22): 1770–9. https://doi.org/10.1136/heartjnl-2014-305783
  12. Crowley M. J., Zullig L. L., Shah B. R., et al. Medication non-adherence after myocardial infarction: an exploration of modifying factors. Journal of General Internal Medicine. 2015; 30(1): 83–90. https://doi.org/10.1007/s11606-014-3072-x
  13. Stephenson J. J., Shinde M. U., Kwong W. J. et al. Comparison of claims vs patient-reported adherence measures and associated outcomes among patients with nonvalvular atrial fibrillation using oral anticoagulant therapy. Patient Preference and Adherence. 2018; (12): 105–117. https://doi.org/10.2147/PPA.S148697
  14. Pacleb A., Lowres N., Randall S. et al. Adherence to Cardiac Medications in Patients with Atrial Fibrillation: A Pilot Study. Heart, Lung and Circulation. 2020; 29(7): e131-e139. https://doi.org/10.1016/j.hlc.2019.11.012
  15. January C. T., Wann L. S., Calkins H, et al. 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients with Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration with the Society of Thoracic Surgeons. Circulation. 2019; 140(2): e125-e151. https://doi.org/10.1161/CIR.0000000000000665
  16. Aliot E., Breithardt G., Brugada J.et al. An international survey of physician and patient understanding, perception, and attitudes to atrial fibrillation and its contribution to cardiovascular disease morbidity and mortality. EP Europace. 2010; 12(5): 626–633. https://doi.org/10.1093/europace/euq109
  17. Thomson P., Rushworth G. F., Andreis F. et al. Longitudinal study of the relationship between patients’ medication adherence and quality of life outcomes and illness perceptions and beliefs about cardiac rehabilitation. BMC Cardiovascular Disorders. 2020; 20(1): 71 p. https://doi.org/10.1186/s12872-020-01378-4
  18. Ho P. M., Lambert-Kerzner A., Carey E. P. et al. Multifaceted intervention to improve medication adherence and secondary prevention measures after acute coronary syndrome hospital discharge: a randomized clinical trial. JAMA Internal Medicine. 2014; 174(2): 186–193. https://doi.org/10.1001/jamainternmed.2013.12944



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