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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.2" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">Вестник восстановительной медицины</journal-id><journal-title-group><journal-title>Вестник восстановительной медицины</journal-title></journal-title-group><issn publication-format="print">2078-1962</issn><issn publication-format="electronic">2713-2625</issn><publisher><publisher-name>National Medical Research Center for Rehabilitation and Balneology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">632112</article-id><article-id pub-id-type="doi">10.38025/2078-1962-2024-23-1-49-55</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group><subj-group><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Сравнение влияния интервальных и непрерывных физических тренировок на индекс качества мышц и функциональную способность у пациентов, находящихся на гемодиализе. Проспективное рандомизированное клиническое исследование</article-title></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-4117-7835</contrib-id><name name-style="eastern" xml:lang="ru"><surname>Мансур</surname><given-names>Х. С.</given-names></name><email>hadeer.elsharkawy90@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-7261-8136</contrib-id><name name-style="eastern" xml:lang="ru"><surname>Эльнахас</surname><given-names>Н. Г.</given-names></name><email>hadeer.elsharkawy90@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="eastern" xml:lang="ru"><surname>Эзз Эльдин</surname><given-names>Х. М.</given-names></name><email>hadeer.elsharkawy90@gmail.com</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-4301-953X</contrib-id><name name-style="eastern" xml:lang="ru"><surname>Ахмед</surname><given-names>Т. Ф.</given-names></name><email>hadeer.elsharkawy90@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-8377-0109</contrib-id><name name-style="eastern" xml:lang="ru"><surname>Шарабаш</surname><given-names>А. М.</given-names></name><email>hadeer.elsharkawy90@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff id="aff-1">Каирский университет</aff><aff id="aff-2">Мэйский университет в Каире</aff><aff id="aff-3">Национальный институт урологии и нефрологии</aff><pub-date date-type="pub" iso-8601-date="2024-05-17" publication-format="electronic"><day>17</day><month>05</month><year>2024</year></pub-date><volume>23</volume><issue>1</issue><fpage>49</fpage><lpage>55</lpage><history><date date-type="received" iso-8601-date="2024-05-16"><day>16</day><month>05</month><year>2024</year></date></history><permissions><copyright-statement>Copyright © 2024, Мансур Х.С., Эльнахас Н.Г., Эзз Эльдин Х.М., Ахмед Т.Ф., Шарабаш А.М.</copyright-statement><copyright-year>2024</copyright-year></permissions><abstract>&lt;p&gt;&lt;bold&gt;ВВЕДЕНИЕ.&lt;/bold&gt; Хроническая болезнь почек (ХБП) является важной проблемой здравоохранения во всем мире, заболеваемость которой растет. Это приводит к возникновению «эпидемии». Общая мышечная слабость у пациентов, находящихся на гемодиализе, обычно поражает нижние конечности и проксимальные мышцы. Пациенты испытывают снижение физической выносливости и качества жизни. Этим людям назначаются физические упражнения для улучшения их физического здоровья и предотвращения последствий заболеваний.&lt;/p&gt;&#13;
&lt;p&gt;&lt;bold&gt;ЦЕЛЬ.&lt;/bold&gt; Определить влияние интервальных и непрерывных физических тренировок на индекс качества мышц и функциональную способность у пациентов, находящихся на гемодиализе.&lt;/p&gt;&#13;
&lt;p&gt;&lt;bold&gt;МАТЕРИАЛЫ И МЕТОДЫ.&lt;/bold&gt; 60 мужчин с хронической почечной недостаточностью 5-й степени, находящихся на гемодиализе, в возрасте от 45 до 55 лет были разделены на две группы с использованием компьютерной блочной рандомизации: в группы (А) и (Б) вошли по 30 пациентов в каждой. Они прошли 8-недельную программу высокоинтенсивных интервальных тренировок (ВИИТ), непрерывных тренировок с вращением педалей средней интенсивности, а также гемодиализ три раза в неделю. Всем пациентам была проведена предварительная и последующая оценка теста на 6-минутную ходьбу (6ТШХ) и индекса качества мышц (ИКМ).&lt;/p&gt;&#13;
&lt;p&gt;&lt;bold&gt;РЕЗУЛЬТАТЫ.&lt;/bold&gt; В обеих группах наблюдалось значительное положительное улучшение показателей ИКМ и 6ТШХ с различными пропорциями, у пациентов, получавших ВИИТ с вращением педалей, наблюдалось незначительное улучшение показателей ИКМ по сравнению с группой непрерывных тренировок средней интенсивности. В группе тренировок средней интенсивности наблюдалось более значительное улучшение в 6ТШХ по сравнению с группой тренировок высокой интенсивности.&lt;/p&gt;&#13;
&lt;p&gt;&lt;bold&gt;ЗАКЛЮЧЕНИЕ.&lt;/bold&gt; Как ВИИТ, так и тренировки средней интенсивности являются практически применимыми хорошими вариантами для людей с ХБП и параллельно улучшают функциональные возможности, качество скелетных мышц и общее качество жизни.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>hemodialysis</kwd><kwd>intradialytic training</kwd><kwd>muscle quality index</kwd><kwd>6MWT</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гемодиализ</kwd><kwd>тренировка для диализных пациентов</kwd><kwd>индекс качества мышц</kwd><kwd>6ТШХ</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Delles C., Vanholder R. Chronic kidney disease. Clinical Science. 2017; 131(3): 225–6. https://doi.org/10.1042/CS20160624</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Androga L., Sharma D., Amodu A., et al. Sarcopenia, obesity, and mortality in US adults with and without chronic kidney disease. Kidney International Reports. 2017; 2(2): 201–11. https://doi.org/10.1016/j.ekir.2016.10.008</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Roshanravan B., Jorge G. and Kenneth W. Exercise and CKD: Skeletal Muscle Dysfunction and Practical Application of Exercise to Prevent and Treat Physical Impairments in CKD. American Journal of Kidney Diseases. 2017; 69(6): 837–52. https://doi.org/10.1053/j.ajkd.2017.01.051</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Manfredini F., Lamberti N. Performance assessment of patient on dialysis. Kidney and Blood Pressure Research. 2014; 39: 176–9. https://doi.org/10.1159/000355794</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Cha RH., Lee G.S., Yoo J.Y., et al. Hand Grip and Leg Muscle Strength in Hemodialysis Patients and Its Determinants. The Journal of Korean Medical Science. 2021; 36(11): e76. https://doi.org/10.3346/jkms.2021.36.e76</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Matsuzawa R., Matsunaga A., Wang G., et al. Relationship between lower extremity muscle strength and all-cause mortality in Japanese patients undergoing dialysis. Physical Therapy. 2014; 94(7): 947–56. https://doi.org/10.2522/ptj.20130270</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Jerez-Mayorga, D., Delgado-Floody P., Intelangelo, L., et al. Behavior of the muscle quality index and isometric strength in elderly women. Physiology &amp; Behavior. 2020: 227. https://doi.org/10.1016/j.physbeh.2020.113145</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Takai Y., Ohta M., Akagi R., et al. Sit-to-stand test to evaluate knee extensor muscle size and strength in the elderly: a novel ap-proach. Journal of Physiological Anthropology. 2009; 28: 123–8. https://doi.org/10.2114/jpa2.28.123</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Wilkinson T., Shur N. and Smith A. “Exercise as medicine” in chronic kidney disease. Scandinavian Journal of Medicine and Science in Sports. 2016; 26(8): 985–8. https://doi.org/10.1111/sms.12714</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Nagano A., Wakabayashi H., Maeda K., et al. Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment. The Journal of nutrition, health and aging. 2021; 25(4): 507–15. https://doi.org/10.1007/s12603-021-1587-5</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Deligiannis A., D’Alessandro C. and Cupisti A. Exercise training in dialysis patients: impact on cardiovascular and skeletal muscle health. Clinical Kidney Journal. 2021; 14(Suppl 2): ii25–ii33. https://doi.org/10.1093/ckj/sfaa273</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Karvonen M., Kentala E., Mustala O. The effects of training on heart rate. A longitudinal study. Annals of Medicine and Experimental Biology Fenn. 1957; 35: 307–15.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Tanaka H., Monahan Seals D.R. Age-predicted maximal heart rate revisited. Journal of the American College of Cardiology. 2001; 37: 153–6. https://doi.org/10.1016/S0735-1097(00)01054-8</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Koufaki P., Kouidi E. Current best evidence recommendations on measurement and interpretation of physical function in patients with chronic kidney disease. Sports Medicine. 2010; 40: 1055–74. https://doi.org/10.2165/11536880-000000000-00000</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Young H.M., March D.S., Graham-Brown M.P., et al. Effects of intradialytic cycling exercise on exercise capacity, quality of life, physical function and cardiovascular measures in adult hemodialysis patients: a systematic review and meta-analysis. Nephrology Dialysis Transplantation. 2018; 33(8): 1436–45. https://doi.org/10.1093/ndt/gfy045</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Song Y., Chen L., Wang M., et al. The optimal exercise modality and intensity for hemodialysis patients incorporating Bayesian network meta-analysis and systematic review. Frontiers in Physiology. 2022; 13: 945465. https://doi.org/10.3389/fphys.2022.945465</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Yeh M.L., Wang M.H., Hsu C.C., Liu Y.M. Twelve-week intradialytic cycling exercise improves physical functional performance with gain in muscle strength and endurance: a randomized controlled trial. Clinical Rehabilitation. 2020; 34(7): 916–26. https://doi.org/10.1177/0269215520921923</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Manfredini F., Mallamaci F., D’Arrigo G., et al. Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial. Journal of the American Society of Nephrology. 2017; 28: 1259–68. https://doi.org/10.1681/ASN.2016030378</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Bae Y.H., Lee S.M., and Jo J.I. Aerobic training during hemodialysis improves body composition, muscle function, physical performance, and quality of life in chronic kidney disease patients. Journal of Physical Therapy Science. 2015; 27(5): 1445–9. https://doi.org/10.1589/jpts.27.1445</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Henrique D.M., Reboredo Mde M., Chaoubah A., Paula R.B. Treinamento aeróbico melhora a capacidade funcional de pacientes em hemodiálise crônica [Aerobic exercise improves physical capacity in patients under chronic hemodialysis]. Arquivos Brasileiros de Cardiologia. 2010; 94(6): 823–8. https://doi.org/10.1590/S0066-782X2010005000043</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Nilsson B.B., Bunæs-Næss H., Edvardsen E., Stenehjem A.E. High-intensity interval training in hemodialysis patients: a pilot randomized controlled trial. BMJ Open Sport &amp; Exercise Medicine. 2019; 5(1): e000617. https://doi.org/10.1136/bmjsem-2019-000617</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Rouchon M.I., Coutard C., Matysiak M., et al. MO068 high intensity interval training improves physical functioning, inflammation and quality of life in peritoneal dialysis patients. Nephrology Dialysis Transplantation. 2016; 31(1): i58. https://doi.org/10.1093/ndt/gfw142.05</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Beetham K.S., Howden E.J., Fassett R.G., et al. High-intensity interval training in chronic kidney disease: A randomized pilot study. Scandinavian Journal of Medicine and Science in Sports. 2019; 29(8): 1197–204. https://doi.org/10.1111/sms.13436</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Larsen S., Danielsen J.H., Søndergård S.D., et al. The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue. Scandinavian Journal of Medicine and Science in Sports. 2015; 25(1): e59–e69. https://doi.org/10.1111/sms.12252</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Li J., Li Y., Atakan M.M., et al. The Molecular Adaptive Responses of Skeletal Muscle to High-Intensity Exercise/Training and Hypoxia. Antioxidants (Basel). 2020; 9(8): 656. https://doi.org/10.3390/antiox9080656</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>Storer T.W., Casaburi R., Sawelson S., Kopple J.D. Endurance exercise training during hemodialysis improves strength, power, fatigability and physical performance in maintenance hemodialysis patients. Nephrology Dialysis Transplantation. 2005; 20(7): 1429–37. https://doi.org/10.1093/ndt/gfh784</mixed-citation></ref><ref id="B27"><label>27.</label><mixed-citation>Liu Q., Gao J., Deng J., Xiao J. Current Studies and Future Directions of Exercise Therapy for Muscle Atrophy Induced by Heart Failure. Frontiers in Cardiovascular Medicine. 2020; 7: 593429. https://doi.org/10.3389/fcvm.2020.593429</mixed-citation></ref><ref id="B28"><label>28.</label><mixed-citation>Fyfe J.J., Bishop D.J., Zacharewicz E., et al. Concurrent exercise incorporating high-intensity interval or continuous training modulates mTORC1 signaling and microRNA expression in human skeletal muscle. American journal of physiology. Regulatory, integrative and comparative physiology. 2016; 310(11): R1297–1311. https://doi.org/10.1152/ajpregu.00479.2015</mixed-citation></ref><ref id="B29"><label>29.</label><mixed-citation>Caparrós-Manosalva C., Garrido-Muñoz N., Alvear-Constanzo B., et al. Effects of high-intensity interval training on lean mass, strength, and power of the lower limbs in healthy old and young people. Frontiers in Physiology. 2023; 14: 1223069. https://doi.org/10.3389/fphys.2023.1223069</mixed-citation></ref><ref id="B30"><label>30.</label><mixed-citation>Ballesta-García I., Martínez-González-Moro I., Rubio-Arias J., Carrasco-Poyatos M. High-intensity interval training versus moderate-intensity continuous training on functional ability and body mass index in middle-aged and older women: a randomized controlled trial. International Journal of Environmental Research and Public Health. 2019; 16(21): 4205. https://doi.org/10.3390/ijerph16214205</mixed-citation></ref></ref-list></back></article>
