Bulletin of Rehabilitation MedicineBulletin of Rehabilitation Medicine2078-19622713-2625National Medical Research Center for Rehabilitation and Balneology63261310.38025/2078-1962-2024-23-2-7-16Research ArticleArticlesRehabilitation of cardiological patients with post-COVID syndrome: morphofunctional data reporthttps://orcid.org/0000-0003-1928-3218SobirovaGuzal N.info@tma.uzhttps://orcid.org/0000-0002-0361-4898MasieroStefanoinfo@tma.uzhttps://orcid.org/0000-0001-6124-6803UsmankhodjayevaAdibakhon A.info@tma.uzhttps://orcid.org/0000-0003-4798-9402BekchanovaMakhfuza R.info@tma.uzhttps://orcid.org/0000-0002-5260-2121DeminNikita A.deminnic1@gmail.comTashkent Medical Academy (TMA)University of PaduaKimyo International University in Tashkent240520242327162405202424052024Copyright © 2024, Sobirova G.N., Masiero S., Usmankhodjayeva A.A., Bekchanova M.R., Demin N.A.2024<p><bold>INTRODUCTION.</bold> Post-COVID is a common complication of COVID-19, occurring in more than a third of patients, and condition will persist for more than 3 months after infection with the SARS-CoV-2.</p> <p><bold>AIM.</bold> To evaluate impact and potential effectiveness of a comprehensive physical rehabilitation program on health of cardiac patients with complications of a previously suffered new coronavirus infection SARS-CoV-2 COVID-19.</p> <p><bold>MATERIALS AND METHODS.</bold> The study involved 128 cardiology patients with post-COVID syndrome. The study participants comprised three groups depending on the 12-week physical rehabilitation program. The effectiveness of rehabilitation was assessed through parameters of cardiopulmonary testing, as well as the 6-minute walk exercise test and the degree of dyspnea according to modified mMRC dyspnea questionnaire.</p> <p><bold>RESULTS.</bold> The mMCR index in CPR group was 1.0 [0.0–1.0] point, compared with 2.0 [1.0–2.0] in control and comparative groups (<italic>p </italic>0.05); exercise tolerance VO<sub>2max</sub> increased by 8.3 ± 3.8 % (<italic>p</italic> 0.05); normalization of heart rate and blood pressure in response to physical activity after 12 weeks in intervention group was 5.0 ± 2.1 % compared to comparative and control groups; 6MWT test results 688 m, in the intervention group, versus 490 m, for participants in control group (<italic>p </italic>0.05).</p> <p><bold>DISCUSSION.</bold> A comparative analysis of previously conducted studies confirmed pattern between the inclusion of combined cardiorespiratory training in the protocol for 12-week rehabilitation of post-COVID complications among cardiac patients, and a decrease in the degree of shortness of breath, as well as an increase in exercise tolerance.</p> <p><bold>CONCLUSIONS.</bold> Based on experimental data obtained, it is advisable to analyze the effects of Cardiopulmonary Physical Rehabilitation program in the framework of larger randomized clinical trials. 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