Issue 4-86, 2018

New approaches to complex treatment of the syndrome of intestinal insufficiency as an important component of post-aggressive rehabilitation of surgical patients in critical condition

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1 Ivanova G.Ye., 2 Popova T.S., 3 Shestopalov A.E., 2 Tropskaya N.S., 2 Matkevich V.A., 2 Vladimirova E.S., 2 Ryk А.А., 2 Kislyakova Е.А., 2 Botin А.S., 2 Kislitsyna O.S., 2 Vilkova I.G.

1 Pirogov Russian National Research Medical University (RNRMU), Moscow, Russia
2 N.V. Sklifosovsky Research Institute for Emergency Medicine of the Moscow Healthcare Department, Moscow, Russia
3 Russian Medical Academy of Postgraduate Education of Ministry of Health and Social Development of Russian Federation, Moscow, Russia


ABSTRACT

The review presents the main modern achievements in the field of complex treatment of the syndrome of intestinalinsufficiency as a rather frequent complication of acute surgical diseases and traumatic abdominal injuries, which largelydetermines the outcome of therapeutic care. The review analyzed a pathogenetic modern concepts concerning combinedand consistent use innovative technologies in the intensive care medicine of the syndrome of intestinal insufficiency in patientsin a critical state. The proposed methodology, tested in the experiment and clinic, found high efficiency and confirmedthe necessity of using in the early postoperative period naso-intestinal intubation and decompression of the gastrointestinaltract, intestinal lavage with a chyme-like glucose-salt enteral solution, enterosorption, a modern prokinetic drugs withstimulating and regulating mechanisms of action, pharmaco-nutrients and enteral nutrition, as well as prebiotics, probioticsand metabiotics.


KEYWORDS: syndrome of intestinal insufficiency, gastric and intestinal lavage, enterosorption, prokinetic drugs, pharmaco-nutrients, prebiotics, probiotics, metabiotics.


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