Issue №5-87, 2018
Changes in Blood Pressure in Different Vascular Beds in Healthy Volunteers During a Passive Orthostatic Test 60º
1 Dorogovtsev V.N., 1 Grechko A.V., 2 Milyagin V.A., 2 Punin D.A., 1 Stepanuk T.A.
1 Federal Scientific and Clinical Center for Reanimatology and Rehabilitation
2 Smolensk State Medical University of the Ministry of Health of the Russian Federation
ABSTRACT
The aim of this study was to evaluate the orthostatic changes in different vascular beds BP indicators and PWV in 40healthy young volunteers in passive tilting 60º. In horizontal position, at rest, the foot artery BP is significantly higher thanbrachial one. Tilt up at 60º does not cause significant changes in the brachial BP, while in the distal artery there is a significantincreasing in SBP and DBP and a decreasing in PBP with a simultaneous increasing in PWV. The influence of the gender factoron orthostatic changes in blood pressure and PWV was revealed.The height has a significant effect on the increasing in blood pressure in distal parts of the vasculature during tilt up, butpractically does not influence on the PWV in the horizontal and tilt up positions of the subjects.
KEYWORDS: systolic blood pressure, diastolic arterial pressure, pulse blood pressure, pulse wave velocity, passive orthostatic test, healthy volunteers, risk factors for cardiovascular diseases
References:
- Kenny R.A., Bayliss J., Ingram A., Sutton R. Head-up tilt: a useful test for investigating unexplained syncope. Lancet. 1986 Jun 14;1(8494):1352-5.
- Rowell LB. Human Cardiovascular Control. Cambridge, MA:Oxford Univ. Press, 1993.
- Gauer OH, Thron HL. Postural changes in the circulation. In: Handbook of Physiology. Circulation, sect. 2, vol. III. Bethesda, MD: American Physiological Society, 1965, p. 2409-2439.
- Kamiya,A.,Kawada,T.,Shimizu,S.,Iwase,S.,Sugimachi,M.,and Tadaaki Mano,T. Slow head-up tilt causes lower activation of muscle sympathetic nerve activity: loading speed-dependence of orthostatic sympathetic activation in humans. Am.J.Physiol.HeartCirc.Physiol. 2009 297, H53-H58.
- Kamiya A, Kawada T, Sugimachi M. Systems physiology of the baroreflex during orthostatic stress: from animals to humans. Front Physiol. 2014 Jul 8;5:256.
- Dorogovcev V.N., Grechko A.V. Znachenie ortostaticheskih izmenenij krovoobrashcheniya v razvitii sosudistyh narushenij. ZH. Klin. Med. 2017; 95(11), 977-986.
- Kario, K. Nat. Rev. Orthostatic hypertension—a new hemodynamic cardiovascular risk factor. Nephrol. 2013;9, 726-738.
- Mosnaim AD, Abiola R, Wolf ME, Perlmuter LC. Etiology and risk factors for developing orthostatic hypotension. Am J Ther. 2010 Jan-Feb;17(1):86-91.
- Jones CD, Loehr L, Franceschini N, Rosamond WD, Chang PP, Shahar E, Couper DJ, Rose KM. Orthostatic hypotension as a risk factor for incident heart failure: the atherosclerosis risk in communities study. Hypertension. 2012 May;59(5):913-8.
- Thomas R.J. et al. Positional change in blood pressure and 8-year risk of hypertension: the CARDIA Study. Mayo Clin. Proc. 2003; Aug;78(8):951-958.
- Kario K Orthostatic hypertension: a measure of blood pressure variation for predicting cardiovascular risk. Circ J. 2009 Jun;73(6):1002-7.
- Rose KM1, Holme I, Light KC, Sharrett AR, Tyroler HA, Heiss G. Association between the blood pressure response to a change in posture and the 6-year incidence of hypertension: prospective findings from the ARIC study. J Hum Hypertens. 2002 Nov;16(11):771-7.
- Dorogovtsev V. Gravitation in a Pathogeny of the Essential Hypertension. Journal of Gravitational Physiology. 2004,July; 11(2):P75-78.
- Fu Q, Shook RP, Okazaki K, Hastings JL, Shibata S, Conner CL, Palmer MD, Levine BD. Vasomotor sympathetic neural control is maintained during sustained upright posture in humans. J Physiol. 2006 Dec 1;577(Pt 2):679-87.
- Patel K, Rossler A, Lackner HK, Trozic I, Laing C, Lorr D, Green DA, Hinghofer-Szalkay H, Goswami N. Effect of postural changes on cardiovascular parameters across gender. Medicine (Baltimore). 2016 Jul;95(28):e4149.
- Smith J, Porth C, Erickson M. Hemodynamic response to the upright posture. J Clin Pharmacol. 1994 May;34(5):375-86.
- Hasegawa M, Rodbard S. Effect of posture on arterial pressures, timing of the arterial sounds and pulse wave velocities in the extremities. Cardiology. 1979;64(2):122-32.
- Osner A. Jr., Colp R. Jr., Burche G.E. Normal blood pressure in the superficial venous system of man at rest in the supine position. Circulation. 1951 May;3(5):674-80.
- Safar ME, Levy BI, Struijker-Boudier H. Current perspectives on arterial stiffness and pulse pressure in hypertension and cardiovascular diseases. Circulation. 2003;107:2864-2869.
- Rotaru C, Liaudet L, Waeber B, Feihl F. Impact of body tilt on the central aortic pressure pulse. Physiol Rep. 2015 Apr;3(4). pii: e12360. doi: 10.14814/ phy2.12360.
- Murabito JM, Evans JC, Larson MG, Nieto K, Levy D, Wilson PW. The ankle-brachial index in the elderly and risk of stroke, coronary disease, and death: the Framingham Study. Arch Intern Med. 2003;163:1939-42. doi: 10.1001/archinte.163.16.1939.
- Rac-Albu M, Iliuta L, Guberna SM, Sinescu C. The role of ankle-brachial index for predicting peripheral arterial disease. Journal of Clinical Medicine 2014; 9(3): 295-302.
- Sundblad P, Spaak J, Kaijser L. Time courses of central hemodynamics during rapid changes in posture. J Appl Physiol (1985). 2014 May 1;116(9):1182-8.
- Thrasher, T. N. Baroreceptor regulation of vasopressin and renin secretion: low-pressure versus high-pressure receptors. Front. Neuroendocrinol. 15: 157-196, 1994.
- Jarvis S, Shibata S, Okada Y, Levine B, Fu Q. Neural-humoral responses during head-up tilt in healthy young white and black women. Front Physiol. 2014 Mar 4;5:86. doi: 10.3389/fphys.2014.00086. eCollection 2014.
- Jardine D, Melton I, Crozier I, Bennett S, Donald R, Ikram H. Neurohormonal response to head-up tilt and its role in vasovagal syncope. Am J Cardiol. 1997 May 1;79(9):1302-6.
- Voors AW, Harsha DW, Webber LS, Berenson GS. Relation of blood pressure to stature in healthy young adults. Am J Epidemiol 115: 833-840,1982.
- Arvedsen SK, Damgaard M, Norsk P. Body height and blood pressure regulation in humans during anti-orthostatic tilting. Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R984-9. doi: 10.1152/ajpregu.00036.2011.
- Mensah GA, Wei GS, Sorlie PD, Fine LJ, Rosenberg Y, Kaufmann PG, Mussolino ME, Hsu LL, Addou E, Engelgau MM, Gordon D. Decline in Cardiovascular Mortality: Possible Causes and Implications. Circ Res. 2017 Jan 20;120(2):366-380. doi: 10.1161/CIRCRESAHA.116.309115.
- 2013 ESH/ESC guidelines for the management of arterial hypertension: the Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2013 Jul;34(28):2159-219. doi: 10.1093/eurheartj/eht151.
- Phillips RA, Xu J, Peterson LE, Arnold RM, Diamond JA, Schussheim AE. Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension. J Am Coll Cardiol. 2018 Mar 2. pii: S0735-1097(18)33226-1. doi: 10.1016/j.jacc.2018.01.074.
- Glasser SP, Halberg DL, Sands C, Gamboa CM, Muntner P, Safford M. Is pulse pressure an independent risk factor for incident acute coronary heart disease events? The REGARDS study. Am J Hypertens. 2014 Apr;27(4):555-63. doi: 10.1093/ajh/hpt168.
©
This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.