Issue №4-98, 2020

Review article

Background to the Use of Plasmapheresis in Complex Therapy and Rehabilitation of Oncologic Patients



1 ORCIDGilmutdinova I.R., 1 ORCIDEremin P.S.

1 National Medical Research Center of Rehabilitation and Balneology, Moscow, Russian Federation


ABSTRACT

Introduction. Oncological diseases take the second place in the world in mortality rate after cardiovascular pathology. Thedevelopment of the tumor is accompanied by the appearance and accumulation of a number of pathological metabolites. Atthe same time, it is worth noting that the expansion of indications for the use of surgical methods of treatment, as well as anincrease in the range of medicated antitumor drugs, especially against the background of combination therapy, is still accompaniedby aggressive effects on the patient's body. Thus, the consequences of radiation and chemotherapy are quite significantand consist of the cumulation of cytotoxic drugs that are toxic not only for tumor cells, but also for other tissue structuresof the body. In this connection, intensive therapy of endogenous intoxication in case of tumor lesions is one of the complexinterdisciplinary problems, in which should participate surgeons, resuscitators, pathophysiologists, transfusiologists.Purpose. Analysis of literature data on the use of plasmapheresis as an effective component of rehabilitation measuresfrom the point of view of pathophysiology in cancer patients.Conclusion. Considering the possibility of using extracorporeal detoxification methods in the treatment andrehabilitation of cancer patients, it should be noted that, against the background of chemotherapy and/or radiationtherapy, plasmapheresis is one of the most common indications for use. Positive responses after plasmapheresis havebeen reported in patients with carcinoma of the lung, colon and breast. In addition, there are reports of the effectivenessof the method in patients with melanoma, head and neck tumors, lymphomas, leukemia and Kaposi’s sarcoma withacquired immunodeficiency. However, there is currently a limited number of studies aimed at the effectiveness of the useof extracorporeal detoxification in the complex treatment of cancer patients.


KEYWORDS: plasmapheresis, oncology, cancer rehabilitation

For citation: Gilmutdinova I.R., Eremin P.S. Background to the Use of Plasmapheresis in Complex therapy and Rehabilitation of Oncologic Patients. Bulletin of Rehabilitation Medicine. 2020; 4 (98): 131–134. https://doi.org/10.38025/2078-1962-2020-98-4-131-134



References:




Creative Commons License
The content is available under the Creative Commons Attribution 4.0 License.

©

Эта статья открытого доступа по лицензии CC BY 4.0. Издательство: ФГБУ «НМИЦ РК» Минздрава России.
This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.

РЕКЛАМА