Issue 23-2, 2024

Original article

https://doi.org/10.38025/2078-1962-2024-23-2-7-16

Rehabilitation of Cardiological Patients with Post-COVID Syndrome: Morphofunctional Data Report

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1 ORCID Guzal N. Sobirova, 2 ORCID Stefano Masiero, 1 ORCID Adibakhon A. Usmankhodjayeva, 3 ORCID Makhfuza R. Bekchanova, 1 ORCID Nikita A. Demin

1 Tashkent Medical Academy (TMA), Tashkent, Republic of Uzbekistan 
2  University of Padua, Padua, Italy 
3  Kimyo International University in Tashkent, Tashkent, Republic of Uzbekistan


ABSTRACT

INTRODUCTION. Post-COVID is a common complication of COVID-19, occurring in more than a third of patients, and condition will persist for more than 3 months after infection with the SARS-CoV-2.
AIM. To evaluate impact and potential effectiveness of a comprehensive physical rehabilitation program on health of cardiac patients with complications of a previously suffered new coronavirus infection SARS-CoV-2 COVID-19.
MATERIALS AND METHODS. The study involved 128 cardiology patients with post-COVID syndrome. The study participants comprised three groups depending on the 12-week physical rehabilitation program. The effectiveness of rehabilitation was assessed through parameters of cardiopulmonary testing, as well as the 6-minute walk exercise test and the degree of dyspnea according to modified mMRC dyspnea questionnaire.
RESULTS. The mMCR index in CPR group was 1.0 [0.0–1.0] point, compared with 2.0 [1.0–2.0] in control and comparative groups (p < 0.05); exercise tolerance VO2max increased by 8.3 ± 3.8 % (p < 0.05); normalization of heart rate and blood pressure in response to physical activity after 12 weeks in intervention group was 5.0 ± 2.1 % compared to comparative and control groups; 6MWT test results 688 m, in the intervention group, versus 490 m, for participants in control group (p < 0.05).
DISCUSSION. A comparative analysis of previously conducted studies confirmed pattern between the inclusion of combined cardiorespiratory training in the protocol for 12-week rehabilitation of post-COVID complications among cardiac patients, and a decrease in the degree of shortness of breath, as well as an increase in exercise tolerance.
CONCLUSIONS. Based on experimental data obtained, it is advisable to analyze the effects of Cardiopulmonary Physical Rehabilitation program in the framework of larger randomized clinical trials. This will allow a more detailed assessment of the clinical consequences, as well as the ability to adjust mode and dose of physical activity of proposed rehabilitation program.


KEYWORDS: COVID-19, post-COVID, cardiorespiratory rehabilitation

FUNDING: The study was carried out within the framework of research grant No. IL-5221091515, Tashkent Medical Academy (2023–2025)

CONFLICT OF INTEREST: The authors declare no apparent or potential conflicts of interest related to the publication of this article.

FOR CITATION:

Sobirova G.N., Masiero S., Usmankhodjaeva A.A., Bekchanova M.R. Demin N.A. Rehabilitation of Cardiological Patients with Post-COVID Syndrome: Morphofunctional Data Report. Bulletin of Rehabilitation Medicine. 2024; 23(2):7-16. https://doi.org/10.38025/2078-1962-2024-23-2-7-16 (In Russ.).

FOR CORRESPONDENCE:

Nikita A. Demin, Е-mail: info@tma.uz, deminnic1@gmail.com


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This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.