Issue 24-3, 2025

Original article

https://doi.org/10.38025/2078-1962-2025-24-3-8-17

Optimising the Timing of Health Resort Treatment in Patients with Arterial Hypertension and Increased Meteosensitivity: a Prospective Study

View article (Download PDF file)



Download XML file

ORCID Tatyana A. Knyazeva1,*, ORCID Irina A. Grishechkina1, ORCID Maksim Yu. Yakovlev1,2, ORCID Elena A. Valtseva3, ORCID Mikhail V. Nikitin1, ORCID Berta Yu. Abramova4, ORCID Alexey V. Chernov5

1 National Medical Research Center for Rehabilitation and Balneology, Moscow, Russia,
2 I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia,
3 F.F. Erisman Federal Scientific Centre of Hygiene, Mytishchi, Russia,
4 Ecology, Health and Quality of Human Life Foundation, Moscow, Russia,
5 Voronezh State Medical University named after N.N. Burdenko, Voronezh, Russia


ABSTRACT

INTRODUCTION.  Arterial hypertension (AH) is a socially significant disease. A significant proportion of patients with AH are weathersensitive, which significantly aggravates the course of the underlying disease.

AIM.  To develop programs for restoring the functional state and adaptive capabilities of patients with arterial hypertension and increased weather sensitivity in order to optimize the duration of their spa treatment.

MATERIALS AND METHODS.  An observational prospective clinical comparative study of 129 patients aged 62 [56; 68] years was conducted for 12 days. The patients were divided into 3 groups. All patients received general sodium chloride baths, gas-air carbon dioxid baths, parafango applications, hyperbaric oxygenation, therapeutic exercises, cognitive-behavioral therapy, and continuous hypotensive drug therapy. Additionally, the first group of patients received dosed aerotherapy together with therapeutic exercises, and the second group received paradoxical breathing exercises using the Strelnikova method. Before and after the course of treatment, anthropometry, peripheral hemodynamics, heart rate variability, and the psychophysiological state of the patients were assessed.

RESULTS AND DISCUSSION.  After completion of treatment, statistically significant differences were obtained in all groups of patients in terms of a decrease in systolic blood pressure (SBP) and an increase in the Well-Being scale scores of the SAN test (according to the Wilcoxon test, p < 0.05). In the first group of patients, after treatment, a statistically significant decrease in elevated pulse pressure, heart rate (HR), integral and frequency indices of heart rate variability (RMSSD, SDNN, LW, IN, PARS) was observed (according to the Wilcoxon test, p < 0.05). Statistically significant differences were revealed between the first and third groups in the level of reduction of initially elevated systolic (U = 54.0, p = 0.02) and pulse BP (U = 55.5, p = 0.023), HR (U = 56.0, p = 0.037), RMSSD, SDNN, LW, IN, PARS (U = 13.0, p = 0.048; U = 34.2, p = 0.033; U = 13.0, p = 0.048; U = 0.0, p = 0.02; U = 48.0, p = 0.033, respectively), and the Well-Being scale of the SAN questionnaire (U = 50.0, p = 0.043).

CONCLUSION.  The study has shown the effectiveness of non-drug treatment programme for AH with increased meteosensitivity, including procedures of aerotherapy and exercise therapy, allowing to optimize the terms of health-resort treatment.


KEYWORDS: aerotherapy, physical exercise, meteosensitivity, hypertension, blood pressure

FOR CITATION:

Knyazeva T.A., Grishechkina I.A., Yakovlev M.Yu., Valtseva E.A., Nikitin M.V., Abramova B. Yu., Chernov A.V. Optimising the Timing of Health Resort Treatment in Patients with Arterial Hypertension and Increased Meteosensitivity: a Prospective Study. Bulletin of Rehabilitation Medicine. 2025; 24(3):8–17. https://doi.org/10.38025/2078-1962-2025-24-3-8-17 (In Russ.). 

FOR CORRESPONDENCE:

Tatyana A. Knyazeva, Е-mail: knyazevata@nmicrk.ru


References:

  1. Баланова Ю.А., Шальнова С.А., Имаева А.Э. и др. Распространенность артериальной гипертонии, охват лечением и его эффективность в Российской Федерации (данные наблюдательного исследования ЭССЕ-РФ-2). Рациональная Фармакотерапия в Кардиологии. 2019; 15(4): 450–466. [Balanova Yu.A., Shalnova S.A., Imaeva A.E., et al. Prevalence, Awareness, Treatment and Control of Hypertension in Russian Federation (Data of Observational ESSE-RF-2 Study) Rational Pharmacotherapy in Cardiology. 2019; 15(4): 450–466. https://doi.org/10.20996/1819-6446-2019-15-4-450-466 https://doi.org/10.20996/1819-6446-2019-15-4-450-466 (In Russ.).]

  2. Викторова И.А., Гришечкина И.А., Стасенко В.Л. и др. Эпидемиологическое исследование ЭССЕ-РФ2 в Омской области: вопросы организации и отклик населения. Профилактическая медицина. 2019; 22(5): 85–90. [Viktorova I.A., Grishechkina I.A., Stasenko V.L., et al. The ESSE-RF2 epidemiological study in the Omsk Region: organization issues and the population’s response. Russian Journal of Preventive Medicine. 2019; 22(5): 85–90. https://doi.org/10.17116/profmed20192205185 https://doi.org/10.17116/profmed20192205185 (In Russ.).]

  3. Баланова Ю.А., Куценко В.А., Шальнова С.А., и др. Взаимосвязь избыточного потребления соли, выявляемого по опросу, с уровнем натрия в моче и артериальным давлением (результаты исследования ЭССЕ) Российский кардиологический журнал. 2020; 25(6): 3791. [Balanova Yu.A., Kutsenko V.A., Shalnova S.A., et al. Correlation of excess salt intake identified by the survey with urine sodium level and blood pressure: data of ESSE-RF study. Russian Journal of Cardiology. 2020;25(6): 3791. https://doi.org/10.15829/1560-4071-2020-3791 https://doi.org/10.15829/1560-4071-2020-3791 (In Russ.).]

  4. Шальнова С.А., Яровая Е.Б., Метельская В.А. и др. Связь артериальной гипертонии, повышенного уровня холестерина липопротеинов низкой плотности и их сочетания с возникновением новых случаев сердечно-сосудистых заболеваний у мужчин и женщин трудоспо­собного возраста. Рациональная Фармакотерапия в Кардиологии. 2024; 20(2): 183–193. [Shalnova S.A., Yarovaya E.B., Metelskaya V.A., et al. The relationship of arterial hypertension, elevated low-density lipoprotein cholesterol and their combination with the occurrence of new cases of cardiovascular diseases in men and women of working age. Rational Pharmacotherapy in Cardiology. 2024; 20(2): 183–193. https://doi.org/10.20996/1819-6446-2024-3013 https://doi.org/10.20996/1819-6446-2024-3013 (In Russ.).]

  5. Liu T., Zhao D., Qi Y. Global Trends in the Epidemiology and Management of Dyslipidemia. J Clin Med. 2022; 11(21): 6377. https://doi.org/10.3390/jcm11216377

  6. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants. Lancet. 2021; 398(10304): 957–980. https://doi.org/10.1016/S0140-6736(21)01330-1

  7. Shreier N.K. The Influence of Weather, Season, Climate, and Disasters on Non-Communicable Diseases. Tampere, Finland: National Institute for Health and Welfare, Finnish University Print Ltd. Research 136. 2014; 92 p.

  8. Уянаева А.И., Погонченкова И.В., Тупицына Ю.Ю. и др. Современная медико-метеорологическая оценка погоды Москвы и эффективность немедикаментозных методов коррекции повышенной метеочувствительности у пациентов с заболеваниями суставов. Вопросы курортологии, физиотерапии и лечебной физической культуры. 2020; 97(5): 60–69. [Uyanaeva A.I., Pogonchenkova I.V., Tupitsyna Y.Y., et al. Modern medical and meteorological assessment of Moscow weather and the effectiveness of non-drug methods of increased meteosensitivity correction in patients with joint diseases. Problems of Balneology, Physiotherapy and Exercise Therapy. 2020; 97(5): 60–69. https://doi.org/10.17116/kurort20209705160 (In Russ.).]

  9. Лян Н.А., Уянаева А.И., Рассулова М.А. и др. Метеопатические реакции и их профилактика у детей с бронхиальной астмой в Московской области: проспективное когортное исследование пациентов с повышенной метеочувствительностью. Вестник восстановительной медицины. 2022; 21 (4): 97–105. [Lyan N.A., Uyanaeva A.I., Rassulova M.A., et al. Meteopathic Reactions and Their Prevention in Children with Bronchial Asthma in the Moscow Region: а Prospective Cohort Study of Patients with High Meteosensitivity. Bulletin of Rehabilitation Medicine. 2022; 21(4): 97–105. https://doi.org/10.38025/2078-1962-2022-21-4-97-105 https://doi.org/10.38025/2078-1962-2022-21-4-97-105 (In Russ.).]

  10. Кисляк О.А., Касатова Т.Б., Постникова С.Л. Коррекция симптомов метеочувствительности у пациентов с артериальной гипертензией. Терапия. 2018; 6(24):111–120. [Kislyak O.A., Kasatova T.B., Postnikov S.L. Correction of symptoms of meteosensitivity in arterial hypertension patients. Therapy. 2018; 6(24):111–120. https://doi.org/10.18565/therapy.2018.6.111-120 https://doi.org/10.18565/therapy.2018.6.111-120 (In Russ.).]

  11. Яковлев М.Ю., Нагорнев С.Н., Уянаева А.И. и др. Изучение связи между влиянием погодных условий и развитием обострений заболеваний системы кровообращения. Вопросы курортологии, физиотерапии и лечебной физической культуры. 2017; 94(S2):164 [Yakovlev M.Yu., Nagornev S.N., Uyanaeva A.I., et al. Studying the relationship between the influence of weather conditions and the development of exacerbations of diseases of the circulatory system. Problems of Balneology, Physiotherapy and Exercise Therapy. 2017; 94(S2):164 (In Russ.)]

  12. Tian Z., Li S., Zhang J., Guo Y. The characteristic of heat wave effects on coronary heart disease mortality in Beijing, China: a time series study. PLoS One. 2013; 9(8): e77321. https://doi.org/10.1371/journal.pone.0077321

  13. Abrignani M.G., Lombardo A., Braschi A., et al. Climatic influences on cardiovascular diseases. World journal of cardiology. 2022; 14 (3): 152–169. https://doi.org/10.4330/wjc.v14.i3.152

  14. Уянаева А.И., Тупицына Ю.Ю., Рассулова М.А. и др. Влияние климата и погоды на механизмы формирования повышенной метеочувствительности (обзор). 2016; 93(5): 52–57. [Uyanaeva A.I., Tupitsyna Iu.Iu., Rassulova M.A., et al. The influence of the climatic and weather conditions on the mechanisms underlying the formation of enhanced meteosensitivity (a literature review). Problems of Balneology, Physiotherapy and Exercise Therapy. 2016; 93(5): 52–57. https://doi.org/10.17116/kurort2016552-57 https://doi.org/10.17116/kurort2016552-57 (In Russ.).]

  15. Barnett A.G., Dobson A.J., McElduff P., et al. WHO MONICA Project. Сold periods and coronary events: an analysis of populations worldwide. J Epid Comm Health. 2005; 59: 551–557. https://doi.org/10.1136/jech.2004.028514

  16. Dasgupta K., Chan С., Da Costa D., et al. Walking behaviour and glycemic control in type 2 diabetes: seasonal and gender Differences-Study design and methods. BMC. Cardiovascular Diabetology. 2007; 6: 1. https://doi.org/10.1186/1475-2840-6-1

  17. Фесюн А.Д., Юрова О.В., Гришечкина И.А. и др. Метеорологические параметры и риск развития гипертонического криза: лон­гитюдное исследование для разработки модели прогнозирования. Вестник восстановительной медицины. 2023; 22(5):54–65. [Fesyun A.D., Yurova O.V., Grishechkina I.A., et al. Meteorological parameters and hypertensive crisis risk: a longitudinal study for developing prediction model. Bulletin of Rehabilitation Medicine. 2023; 22(5): 54–65. https://doi.org/10.38025/2078-1962-2023-22-5-54-65 https://doi.org/10.38025/2078-1962-2023-22-5-54-65 (In Russ.).]

  18. Martinaituene D., Rauskauskiene N. Weather-related subjective well-being in patients with coronary artery disease. International journal of biometeorology. 2021; 65(8): 1299–1312. https://doi.org/10.1007/s00484-020-01942-99

  19. Мухарлямов Ф.Ю., Иванова Е.С., Головунина И.С., Попов С.Н. Программы медицинской реабилитации при постинфарктном кардиосклерозе и артериальной гипертонии. Доктор.Ру. 2011; 8 (67): 18–27. [Muharlyamov F.Yu., Ivanova E.S., Golovunina I.S., Popov S.N. Medical rehabilitation programs for post-infarction cardiosclerosis and arterial hypertension. Doktor.Ru. 2011; 8(67): 18–27 (In Russ.).]

  20. Junjie Xiao. Physical Exercise for Human Health. Advances in Experimental Medicine and Biology. 2020th Edition. 2024; 1128.

  21. Фесюн А.Д., Яковлев М.Ю., Вальцева Е.А. и др. Развитие метеопатических реакций организма у пациентов, находящихся на лечении в сана­торно-курортных организациях. Вестник восстановительной медицины. 2023; 22(1): 36–45. https://doi.org/10.38025/2078-1962-2023-22-1-36-45 [Fesyun A.D., Yakovlev M.Yu., Valtseva E.A., et al. Development of meteopathic reactions in patients treated at Health Resorts: a Cross-Sectional Study of 735 Patients. Bulletin of Rehabilitation Medicine. 2023; 22(1): 36–45. https://doi.org/10.38025/2078-1962-2023-22-1-36-45 (In Russ.)]

  22. Князева Т.А., Абрамова Б.Ю., Гришечкина И.А. и др. Cезонные колебания гемодинамических характеристик у пациен­тов с повышенной метеочувствительностью: анкетный опрос. Вестник восстановительной медицины. 2023; 22(4): 105–113. https://doi.org/10.38025/2078-1962-2023-22-4-105-113 [Knyazeva Т.А. Abramova B.Y., Grishechkina I.A., et al. Seasonal Fluctuations in Hemodynamic Characteristics in Patients with Increased Meteosensitivity: a Survey. Bulletin of Rehabilitation Medicine. 2023; 22(4): 105–113. https://doi.org/10.38025/2078-1962-2023-22-4-105-113 (In Russ.).]

  23. Абрамова Б.Ю., Яковлев М.Ю., Вальцева Е.А., Гришечкина И.А. Эффективность лечебных программ физической активности у пациентов с повышенной метеочувствительностью и риском развития хронических неинфекционных заболеваний. Russian Journal of Environmental and Rehabilitation Medicine. 2024; 2: 69–77 [Abramova B.Yu., Yakovlev M.Yu., Valtseva E.A, Grishechkina I.A. Efficacy of therapeutic physical activity programs in patients with increased meteosensitivity and risk of chronic noncommunicable diseases. Russian Journal of Environmental and Rehabilitation Medicine.2024; 2: 69–77. (In Russ.).]





Creative Commons License
The content is available under the Creative Commons Attribution 4.0 License.

©


This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.