Issue 24-3, 2025

Review

https://doi.org/10.38025/2078-1962-2025-24-3-102-112

Optimising the Timing of Health Resort Treatment in Patients with Arterial Hypertension and Increased Meteosensitivity: a Prospective Study

View article (Download PDF file)



Download XML file

ORCIDBair A. Zhigzhitov1,*, ORCIDLarisa A. Marchenkova1, ORCIDVladimir B. Knyazkov2, ORCIDDaria D. Lebedeva3, ORCIDLev G. Agasarov1,4

1 National Medical Research Center for Rehabilitation and Balneology, Moscow, Russia
2 Russian University of Medicine, Moscow, Russia
3 Central Clinical Hospital of the Administrative directorate of the President of the Russian Federation, Moscow, Russia
4 I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia


ABSTRACT

INTRODUCTION.  The clinically frequently detected combination of ronchopathy (snoring) and obstructive sleep apnea is an important problem in modern medicine. Correction of this pathology is performed surgically with known success, however, in this regard, it is necessary to point out the features of the condition of most patients that prevent surgical intervention, as well as the observed frequency of recurrence of the process. In addition, the importance of transient factors in upper respiratory tract obstruction, which require correction during the acute phase, indicates the prospects for the development of modern therapeutic approaches.

AIM.  To study the effectiveness of the original spectral phototherapy method in the complex treatment of patients with ronchopathy and obstructive sleep apnea syndrome.

MATERIALS AND METHODS.  The study included 90 patients (67 men and 23 women) aged 30 to 75 years with bronchopathy and moderate obstructive sleep apnea. The examination of these individuals was carried out using questionnaires, pharyngoscopy, respiratory monitoring, and biochemical analysis (calculating the balance of a number of trace elements) before, 10 days, and 3 months after treatment. These patients were divided into three groups, each consisting of 30 people. In all groups, standard treatment was performed, including positional therapy, exercises for facial muscles, etc. In group 1, they limited themselves to this, while in group 2, they additionally used intraoral mouthguards, and in group 3, mouthguards and spectral phototherapy were used.

RESULTS AND DISCUSSION.  The data from the questionnaire survey performed after treatment reflected the regression of disease manifestations in patients of all groups, however, with the priority of the third group, the treatment of which included spectral phototherapy. A decrease in the intensity of snoring and a decrease in the number of episodes of sleep apnea with improved sleep quality was noted after 10 days of treatment in 12 patients of the first group, 18 in the second and 21 in the third, and after 3 months of treatment, the preservation of the therapeutic effect was noted in 9 patients of the first group, 11 in the second and 15 in the third, which correlated with an increase in potassium, magnesium, manganese, and calcium, and corresponded to the transition of OSA from moderate to mild.

CONCLUSION.  Spectral phototherapy is an effective method indicated for use in the complex treatment of patients with ronchopathy and obstructive sleep apnea syndrome of moderate severity.


KEYWORDS: neurodevelopmental therapy, Bobath-therapy, children, perinatal nervous system injury, cerebral palsy, neurorehabilitation

FOR CITATION:

Khan M.A., Kostenko E.V., Mikitchenko N.A., Degtyareva M.G., Shungarova Z.H. Outlook for the Use of Neurodevelopmental Therapy in Children with Perinatal Central Nervous System Damage: a Review. Bulletin of Rehabilitation Medicine. 2025; 24(3):102–112. https://doi.org/10.38025/2078-1962-2025-24-3-102-112 (In Russ.). 

FOR CORRESPONDENCE:

Natalya A. Mikitchenko, Е-mail: mikitchenko_nata@mail.ru, 6057016@mail.ru


References:

  1. Киртбая А.Р., Ляпин В.М., Епифанцева А.А. и др. Патоморфологические особенности поражений головного мозга в зависимости от гестационного возраста. Неонатология: новости, мнения, обучение. 2022; 10(1): 16–22. [Kirtbaya A.R., Lyapin V.M., Epifantseva A.A., et al. Pathomorphological features of brain lesions depending on gestational age. Neonatology: news, opinions, training. 2022; 10(1): 16–22. https://doi.org/10.33029/2308-2402-2022-10-1-16-22 https://doi.org/10.33029/2308-2402-2022-10-1-16-22 (In Russ.).]

  2. Шумилов П.В., Мазманян П.А., Саркисян Е.А., Никогосян К.В. Особенности психомоторного развития недоношенных новорожденных с очень низкой и экстремально низкой массой тела при рождении к двухлетнему скорригированному возрасту. Российский вестник перинатологии и педиатрии. 2022. 67(3): 54–60. [Shumilov P.V., Mazmanyan P.A., Sarkisyan E.A., Nikoghosyan K.V. Features of the psychomotor development of premature newborns with very low and extremely low birth weight by the age of two. Russian Bulletin of Perinatology and Pediatrics. 2022. 67(3): 54–60. https://doi.org/10.21508/1027-4065-2022-67-3-54-60 https://doi.org/10.21508/1027-4065-2022-67-3-54-60 (In Russ.).]

  3. Яковлева Т.В., Зелинская Д.И., Туренко О.Ю. Управление детской инвалидностью: медицинские аспекты. Национальное здравоохранение. 2022; 3(1): 5–14. [Yakovleva T.V., Zelinskaya D.I., Turenko O.Y. Management of children’s disability: medical aspects. National healthcare. 2022; 3(1): 5–14. https://doi.org/10.47093/2713-069X.2022.3.1.5-14 https://doi.org/10.47093/2713-069X.2022.3.1.5-14 (In Russ.).]

  4. Заваденко Н.Н, Давыдова Л.А., Заваденко А.Н., Нестеровский Ю.Е. Нарушения неврологического развития детей, рожденных недоношен­ными. Педиатрия. Журнал им. Г.Н. Сперанского. 2023; 102(1): 89–98. [Zavadenko N.N., Davydova L.A., Zavadenko A.N., Nesterovskiy Yu.E. Disorders of neurological development of children born prematurely. Pediatrics. The G.N. Speransky Journal. 2023; 102(1): 89–98. https://doi.org/10.24110/0031-403X-2023-102-1-89-97 https://doi.org/10.24110/0031-403X-2023-102-1-89-97 (In Russ.).]

  5. Finch-Edmondson M., Morgan C., Hunt R.W., Novak I. Emergent Prophylactic, Reparative and Restorative Brain Interventions for Infants Born Preterm with Cerebral Palsy. Front. Physiol. 2019; 10: 15. https://doi.org/10.3389/fphys.2019.00015

  6. Блинов Д.В. Перинатальное поражение мозга: актуальные вопросы эпидемиологии и подходы к классификации. Акушерство, гинекология и репродукция. 2016; 4: 84–93. [Blinov D.V. Perinatal brain damage: current issues of epidemiology and approaches to classification. Obstetrics, gynecology, and reproduction. 2016; 4: 84–93 (In Russ.).]

  7. Глухов, Б.М., Байдарбекова А.К. Исходы заболевания и реабилитационный потенциал у детей с внутрижелудочковыми кровоизлияниями пе­ринатального периода. Журнал неврологии и психиатрии им. C.C. Корсакова. 2021; 121(4): 19–24. [Glukhov B.M., Aidarbekova A.K. Disease outcomes and rehabilitation potential in children with intraventricular hemorrhages of the perinatal period. Korsakov Journal of Neurology and Psychiatry. 2021; 121(4): 19–24. https://doi.org/10.17116/jnevro202112104119 https://doi.org/10.17116/jnevro202112104119 (In Russ.).]

  8. Vo Van P., Alison M., Morel B., et al. Advanced Brain Imaging in Preterm Infants: A Narrative Review of Microstructural and Connectomic Disruption. Children. 2022; 9: 356. https://doi.org/10.3390/children9030356

  9. Крутикова Н.Ю., Давыденкова А.С., Жевнова Е.В., Жевнов Д.И. Комплексная оценка состояния здоровья детей, перенесших перинатальное поражение нервной системы. Смоленский медицинский альманах. 2018; 1: 177–179. [Krutikova N.Yu., Davydenkova A.S., Zhevnova E.V., Zhevnov D.I. Comprehensive assessment of the health status of children who have suffered perinatal damage to the nervous system. Smolensk Medical Almanac. 2018; 1: 177–179 (In Russ.).]

  10. Батышева Т.Т., Быкова О.В., Платонова А.Н. и др. Перинатальные факторы риска детской неврологической инвалидности и способы их коррекции. Фарматека. 2014; 1: 81–86 [Batysheva T.T., Bykova O.V., Platonova A.N., et al. Perinatal risk factors for childhood neurological disability and ways to correct them. Pharmaceutical library. 2014; 1: 81–86 (In Russ.).]

  11. Богомолова И.К., Шильникова Т.Н. Современные клинико-патогенетические аспекты, диагностика и лечение детского церебрального паралича. Забайкальский медицинский вестник. 2023; 3: 68–79. [Bogomolova I.K., Shilnikova T.N. Modern clinical and pathogenetic aspects, diagnosis and treatment of cerebral palsy in children. Zabaikalsky Medical Bulletin. 2023; 3: 68–79. https://doi.org/10.52485/19986173_2023_3_68 https://doi.org/10.52485/19986173_2023_3_68 (In Russ.).]

  12. Колесникова Е.В., Вышлова И.А., Карпов С.М., Соболева О.А. Детский церебральный паралич: современное состояние проблемы (обзор литературы). Русский журнал детской неврологии. 2024; 19(4): 20–28. [Kolesnikova E.V., Vyshlova I.A., Karpov S.M., Soboleva O.A. Cerebral palsy in children: current state of the problem (literature review). Russian Journal of Pediatric Neurology. 2024; 19(4): 20–28. https://doi.org/10.17650/2073-8803-2024-19-4-20-28 https://doi.org/10.17650/2073-8803-2024-19-4-20-28 (In Russ.).]

  13. Сороковикова Т.В., Морозов А.М., Алексанян К.А. и др. Эпилептические приступы, обусловленные гипоксически-ишемическим поражением ЦНС. Вестник неврологии, психиатрии и нейрохирургии. 2024; 17.1(168): 111–119. [Sorokovikova T.V., Morozov A.M., Aleksanyan K.A. et al. Epileptic seizures caused by hypoxic-ischemic damage to the central nervous system. Bulletin of Neurology, Psychiatry and Neurosurgery. 2024; 17.1(168): 111–119. https://doi.org/10.33920/med-01-2401-11 https://doi.org/10.33920/med-01-2401-11 (In Russ.).]

  14. Клещенко Е.И., Шимченко Е. В. Особенности психомоторного развития детей с различными исходами перинатального гипоксического поражения головного мозга. Кубанский научный медицинский вестник. 2019; 26(3): 48–54. [Kleshchenko E.I., Shimchenko E.V. Features of psychomotor development of children with different outcomes of perinatal hypoxic brain damage. Kuban Scientific Medical Bulletin. 2019; 26(3): 48–54. https://doi.org/10.25207/1608-6228-2019-26-3-48-54 https://doi.org/10.25207/1608-6228-2019-26-3-48-54 (In Russ.).]

  15. Петрухин A.C., Созаева H.С. Развитие двигательных функций у здоровых детей первого года жизни. Русский журнал детской неврологии. 2008; 4: 16–25 [Petrukhin A.C., Sozaeva H.S. Development of motor functions in healthy children of the first year of life” Russian Journal of Pediatric Neurology. 2008; 4:16–25 (In Russ.).]

  16. Heineman K.R., Schendelaar P., Van den Heuvel E.R., Hadders-Algra M. Motor development in infancy is related to cognitive function at 4 years of age. Dev Med Child Neurol. 2018; 60(11): 1149–1155. https://doi.org/10.1111/dmcn.13761

  17. Wu Y.C., Heineman K.R., La Bastide-Van Gemert S., et al. Motor behaviour in infancy is associated with neurological, cognitive, and behavioural function of children born to parents with reduced fertility. Dev Med Child Neurol. 2020; 62(9): 1089–1095. https://doi.org/10.1111/dmcn.14520

  18. Rees P., Callan C., Chadda K., et al. School-age outcomes of children after perinatal brain injury: a systematic review and meta-analysis. BMJ Paediatr Open. 2023; 7(1): e001810. https://doi.org/10.1136/bmjpo-2022-001810

  19. Rees P., Callan C., Chadda K.R., et al. Preterm Brain Injury and Neurodevelopmental Outcomes: A Meta-analysis. Pediatrics. 2022; 150(6): e2022057442. https://doi.org/10.1542/peds.2022-057442

  20. Mwaniki M.K., Atieno M., Lawn J.E., Newton C.R. Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review. Lancet. 2012; 379(9814): 445–452. https://doi.org/10.1016/S0140-6736(11)61577-8

  21. Хан М.А., Дегтярева М.Г., Иванова И.И. Методы кинезитерапии в медицинской реабилитации детей с перинатальным поражением центральной нервной системы Физиотерапия, бальнеология и реабилитация. 2022; 21(1): 73–80. [Khan M.A., Degtyareva M.G., Ivanova I.I. Methods of kinesitherapy in medical rehabilitation of children with perinatal central nervous system damage Physiotherapy, balneology and rehabilitation. 2022; 21(1): 73–80. https://doi.org/10.17816/rjpbr107458 https://doi.org/10.17816/rjpbr107458 (In Russ.).]

  22. Хан М.А., Чубарова А.И., Дегтярева М.Г. Современные нелекарственные технологии медицинской реабилитации детей с последствиями перинатального поражения центральной нервной системы. Вопросы курортологии, физиотерапии и лечебной физической культуры. 2020; 97(6): 50–58. [Khan M.A., Chubarova A.I., Degtyareva M.G. Modern non-medicinal technologies of medical rehabilitation of children with the consequences of perinatal damage to the central nervous system. Issues of balneology, physiotherapy and therapeutic physical education. 2020; 97(6): 50–58. https://doi.org/10.17116/kurort20209706150 https://doi.org/10.17116/kurort20209706150 (In Russ.).]

  23. Хан М.А., Прикулс В.Ф., Микитченко Н.А. Физическая реабилитация детей с перинатальным поражением центральной нервной системы. Физиотерапевт. 2021; 3: 29–39. [Khan M.A., Prikul V.F., Mikitchenko N.A. Physical rehabilitation of children with perinatal damage to the central nervous system. Physiotherapist. 2021; 3: 29–39. https://doi.org/10.33920/med-14-2106-04 https://doi.org/10.33920/med-14-2106-04 (In Russ.).]

  24. Лечебная физическая культура в системе медицинской реабилитации: национальное руководство. Под ред. Епифанова В.А., Петровой М.С., Епифанова А.В. Москва: ГЭОТАР-Медиа. 2022; с. 758–770. [Therapeutic physical culture in the medical rehabilitation system: national guidelines. Edited by Epifanov V.A., Petrova M.S., Epifanov A.V. Moscow: GEOTAR-Media. 2022; pp. 758–770 (In Russ.).]

  25. Милькаманович В.К. Бобат-терапия: физиологические и технологические аспекты в реабилитации лиц с нарушениями движения. Медицинские знания. 2021; 1: 10–14. [Milkamanovich V.K. Bobat therapy: physiological and technological aspects in rehabilitation of persons with movement disorders. Medical knowledge. 2021; 1: 10–14 (In Russ.).]

  26. Рейн С., Медоуз Л., Линч-Эллерингтон М. Бобат-концепция. Теория и клиническая практика в неврологической реабилитации. Кириллица. 2013; 320 с. [Rain S., Meadows L., Lynch-Ellrington M. Bobat-concept. Theory and clinical practice in neurological rehabilitation. Cyrillic Alphabet. 2013; 320 p. (In Russ.).]

  27. Parau D., Todoran A.B., Barcutean L., et al. The Benefits of Combining Bobath and Vojta Therapies in Infants with Motor Development Impairment- A Pilot Study. Medicina (Kaunas). 2023; 59(10): 1883. https://doi.org/10.3390/medicina59101883

  28. Te Velde A., Morgan C., Finch-Edmondson M., et al. Neurodevelopmental Therapy for Cerebral Palsy: A Meta-analysis. Pediatrics. 2022; 149(6): e2021055061. https://doi.org/10.1542/peds.2021-055061

  29. Tekin F., Kavlak E., Cavlak U., Altug F. Effectiveness of Neuro-Developmental Treatment (Bobath Concept) on postural control and balance in Cerebral Palsied children. J Back Musculoskelet Rehabil. 2018; 31(2): 397–403. https://doi.org/10.3233/BMR-17081

  30. Kavlak E., Ünal A., Tekin F., Altuğ F. Effectiveness of Bobath therapy on balance in cerebral palsy. Çukurova Med. J. 2018; 43: 975–981. https://doi.org/10.17826/cumj.375565

  31. Хомякова О.В., Короткий П.Ю. Эффективность применения методики Бобат-терапии для детей старшего школьного возраста с детским церебральным параличом. Научный вестник Крыма. 2020; 4(27): 13–19. [Khomyakova O.V., Korotky P.Yu. The effectiveness of the Bobat therapy technique for older school-age children with cerebral palsy. Scientific Bulletin of Crimea. 2020; 4(27): 13–19 (In Russ.).]

  32. Ari G. Randomised controlled study of investigate effects of trunk control training on motor function of children with diplegic cerebral palsy. Fizyoterapi ve Rehabilitasyon Bo¨lu¨mu¨ Tez Koleksiyonu 2015; 105.

  33. Szuflak K., Malak R., Fechner B., et al. The Masticatory Structure and Function in Children with Cerebral Palsy — A Pilot Study. Healthcare 2023; 11: 1029. https://doi.org/10.3390/healthcare11071029

  34. Acar G., Ejraei N., Turkdoğan, D., et al. The Effects of Neurodevelopmental Therapy on Feeding and Swallowing Activities in Children with Cerebral Palsy. Dysphagia 202; 37: 800–811.

  35. Chapman S.D., Farina L., Kronforst K., Dizon M. MicroRNA profile differences in neonates at risk for cerebral palsy. Phys Med Rehabil Int. 2018; 5(3): 1148.

  36. Fortin O., Husein N., Oskoui M., et al. Canadian Cerebral Palsy Registry. Risk Factors and Outcomes for Cerebral Palsy with Hypoxic-Ischemic Brain Injury Patterns Without Documented Neonatal Encephalopathy. Neurology. 2024; 102(6): e208111. https://doi.org/10.1212/WNL.0000000000208111

  37. Novak I., Morgan C., Adde L., et al. Early, accurate diagnosis and early intervention in cerebral palsy: advances in diagnosis and treatment. JAMA pediatrics. 2017; 171(9): 897–907. https://doi.org/10.1001/jamapediatrics.2017.1689

  38. Адулас Е.И. Либерман Л.Н. Нейроразвивающая терапия в реабилитации детей первого года жизни с перинатальной патологией центральной нервной системы. Педиатр. 2017; 8(S1): М29–М30. [Adulas E.I. Lieberman L.N. Neuro-developmental therapy in the rehabilitation of infants with perinatal pathology of the central nervous system. Pediatrician. 2017; 8(S1): M29–M30 (In Russ.).]

  39. Morgan C., Fetters L., Adde L., et al. Early Intervention for Children Aged 0 to 2 Years With or at High Risk of Cerebral Palsy: International Clinical Practice Guideline Based on Systematic Reviews. JAMA Pediatr. 202; 175(8):846–858. https://doi.org/10.1001/jamapediatrics.2021.0878

  40. Novak I., Morgan C. High-risk follow-up: Early intervention and rehabilitation. Handb Clin Neurol. 2019; 162: 483–510. https://doi.org/10.1016/b978-0-444-64029-1.00023-0

  41. Orton J., Doyle L.W., Tripathi T., et al. Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants. Cochrane Database Syst Rev. 2024; 2(2): CD005495. https://doi.org/10.1002/14651858.CD005495.pub5

  42. Martínez Moreno M., Macias Merlo L. Early detection and intervention in cerebral palsy: from knowledge to action. Dev Med Child Neurol. 2022; 64(5): 529. https://doi.org/10.1111/dmcn.15178

  43. Pierrat V., Marchand-Martin L., Arnaud, C., et al. Neurodevelopmental outcome at 2 years for preterm children born at 22 to 34 weeks’ gestation in France in 2011: EPIPAGE-2 cohort study. Br. Med. J. 2017; 358: j3448.

  44. Pierrat V., Marchand-Martin L., Marret S., et al. Neurodevelopmental outcomes at age 5 among children born preterm: EPIPAGE-2 cohort study. Br. Med. J. 2021; 373: n741.

  45. Kałucka A.M., Kałużyński W., Prokop A.M., Kikowski Ł. Physiotherapy of Prematurely Born Children Taking into Account the Degree of Biological Immaturity. Wiadomości Lek. 2022; 75: 2315–2321. https://doi.org/10.36740/WLek202210101

  46. Parau D., Todoran A.B., Balasa R. Physiotherapy Intervention on Premature Infants-A Pilot Study. Medicina (Kaunas). 2024; 60(1): 138. https://doi.org/10.3390/medicina60010138




Creative Commons License
The content is available under the Creative Commons Attribution 4.0 License.

©


This is an open article under the CC BY 4.0 license. Published by the National Medical Research Center for Rehabilitation and Balneology.